Thrift Savings Plan Investing for Beginners | Fresh Articles Daily

The Thrift Savings Plan is a wonderful defined contribution retirement plan for US government employees. But a lot of its members are unsure on how to participate in it and make their investment allocations. While each investor?s situation is unique , and we cannot offer individualized investment advice, what follows are general guidelines which may be useful in reaching your TSP retirement goals.

Determine how much money you need to get you through your retirement years. A good guideline is approximately eighty and 90 percent of your typical yearly expenses. Next, depending on the investing strategy that you choose, figure out a likely average expected return on your investments. Finally, convert this into your required monthly savings amount. Many investment sites on the Internet provide retirement calculators to guide you through these steps.

Determine how much risk you can take. It is extremely important that you pick a portfolio allocation and strategy which is compatible with your ability to tolerate investment volatility and occasional declines in your TSP account value. It is normal to experience some losses during periods of economic decline and bear markets. Failure to match your investment allocation to your risk profile often leads to behavioral investing no-no?s which are all too common, such as selling your risky investments like stocks at the bottom of bear market lows, and buying back in only after prices have risen and recovered substantially.

Decide on an investment approach. Choose whether you would like to be a passive investor or actively manage your investment portfolio. If you choose the former, decide on an appropriate allocation to the available TSP funds (always keeping in mind your own risk profile). If you decide to manage your investments actively, it?s up to you to choose a strategy that is likely to have good performance. As you review the options, look for a long-term performance record and clearly defined strategy rules that you understand. If you?re not sure, then you may be better off sticking to a passive asset allocation or investing your savings in one of the TSP Lifecycle Funds.

Always strive to consistently contribute to your TSP every month. While you?re early in your career and have not yet reached your full earnings potential, it may be challenging to meet your minimum monthly contributions. But take them seriously and cut your living expenses as necessary to meet your savings plan, since this is the best time to accumulate investments, while you?re still a long time away from retiring.

Let your retirement savings grow for as long as possible, to take full advantage of the power of compounding interest. This comes down to two things: start saving as early as you can, and try to avoid making any premature withdrawals before your planned retirement date, because you will owe the IRS a tax penalty on these.

Investors who stick to these principles are on the right track to meeting their Thrift Savings Plan retirement goals.

Learn about the benefits and disadvantages of investing in the Thrift Savings Plan and TSP funds.. Free reprint available from: Thrift Savings Plan Investing for Beginners.

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Tags: Business, business and finance, Investment, Retirement, retirement savings, saving for retirement, Thrift Savings Plan, tsp funds, tsp strategy

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Was the franchising business model a spiritual inspiration? TED ...

?Who invented the franchise?? ? asks this TED Education talk.

The answer it gives might surprise many and it will delight those who have themselves found?that the ?access? spiritual Christianity ? particularly Christian Science -?can give to ?broader and higher realms??can override issues of lacking??access? to temporal power and financial resources. ?

This is an entertaining and educational gem of a story of how one working class woman?s triumphant innovation benefitted thousands of her peers in an era when women were hardly ever business women and when working class people were not generally upwardly mobile.

-

In her textbook detailing the health-giving power of a truly spiritual Christianity, Mary Baker Eddy writes:

The term Science, properly understood, refers only to the laws of God and to His government of the universe, inclusive of man. From this it follows that business men and cultured scholars have found that Christian Science enhances their endurance and mental powers, enlarges their perception of character, gives them acuteness and comprehensiveness and an ability to exceed their ordinary capacity. The human mind, imbued with this spiritual understanding, becomes more elastic, is capable of greater endurance, escapes somewhat from itself, and requires less repose. A knowledge of the Science of being develops the latent abilities and possibilities of man. It extends the atmosphere of thought, giving mortals access to broader and higher realms. It raises the thinker into his native air of insight and perspicacity. (Science and Health with Key to the Scriptures)

Jane Plitt?s biography of?Martha Matilda Harper?- Martha Matilda Harper and the American Dream: How One Woman Changed the Face of Modern Business -?is available at Amazon.

If you like it, please spread the word!

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Poverty, frustration keep Macedonia tensions alive

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Romney gets Bush backing, but no sign of George W.

HOUSTON (AP) ? George W. Bush is as hard to find in his father's office, as he is in the 2012 presidential contest.

The 43rd president appears in a gold-framed picture tucked into a far corner of the room, partially hidden by a Texas flag and a cabinet door. The placement ? whether intentional or not ? is a reminder of the Republican presidential campaign and the lengths to which Romney and his rivals have tried to marginalize the two-term president.

The younger Bush was an afterthought Thursday as former President George H.W. Bush met with current GOP front-runner Mitt Romney until a reporter raised the issue.

"I haven't met with President George W. Bush. We speak from time to time," Romney said when asked if he had sought the younger Bush's endorsement.

Reporters were forced to leave the room before they could ask more about Romney's connection to the Republican president who left office just three years ago with the nation on the brink of financial ruin. George W. Bush has been ignored for months in the Republican presidential campaign. But his absence has been more pronounced over the last seven days as Romney trumpeted the endorsements of the former president's father and younger brother, former Florida. Gov. Jeb Bush, while spending two days courting donors across Texas.

George W. Bush, who lives in Dallas, did not attend any of Romney's half dozen Texas fundraisers this week. And he's not expected to follow his family's migration to Romney's camp any time soon.

While largely unspoken, both sides acknowledge that Republicans would be best served by not reminding voters of the Bush legacy of gaping budget deficits, two wars and record low approval ratings. His eight-year presidency has merited no more than a fleeting reference from Romney and his rivals in debates, campaign stops and interviews.

"For now we're just staying out of it," George W. Bush spokesman Freddy Ford said Thursday, declining to comment on a possible endorsement. Ford said Bush was focused on promoting and developing a presidential library bearing his name at Southern Methodist University.

"That's really where he's spending his time," Ford said.

But George W. Bush's virtual invisibility from the presidential contest seemed to surprise even his 87-year-old father Thursday, as a handful of reporters visited the senior Bush's private office in Houston to watch him endorse Romney.

"Has he endorsed you?" George H.W. Bush quietly asked Romney as reporters were beginning to the leave the room.

"Uh, no, no," Romney responded, before Barbara Bush quickly ended the conversation: "We'll talk about that," the former first lady said.

The 43rd president has been noticeably absent from national politics since leaving office in 2009 with a Gallup approval rating of just 34 percent. His predecessor, Democrat Bill Clinton, had a 66 percent approval rating in early 2001 when he stepped down after two terms marred by a sex scandal and impeachment.

A plurality of Americans continue to blame Bush for the nation's economic struggles: 43 percent of voters said he deserved a lot or almost all of the blame, compared with 36 percent who point to Republicans in Congress, 33 percent who think Democrats in Congress are responsible and 30 percent who credit President Barack Obama, according to a December AP-GfK poll.

In a presidential contest dominated by concerns over the economy, government spending and federal debt, the Republican candidates have been loath to acknowledge the extent to which the George W. Bush administration's policies contributed to those problems.

There is no question that Obama's policies, including the federal stimulus program and the auto industry bailout, have swollen the deficit and deepened the debt. And three years into his presidency, Obama often falls back on complaints about the bad situation he inherited when defending his own economic performance.

But while Obama may be overly eager to blame the Bush years for the nation's problems, GOP presidential contenders seem just as eager to pretend those years never happened.

"George W. Bush is still too fresh in the minds of voters," said Republican operative Michael Dennehy, a top staffer for Sen. John McCain's presidential bid four years ago. "The Democrats' strategy is to try to pin the bad economy on him. ... It's smarter to just avoid being directly drawn into that line of attack right now."

Taking office in 2001 with a balanced federal budget and a surplus in the Treasury, Bush quickly pushed through sweeping tax cuts without nipping expenditures a corresponding amount. The Bush tax cuts were set to expire after 10 years, but Obama allowed them to remain in place temporarily in exchange for an extension of unemployment benefits and a payroll tax cut.

The wars in Iraq and Afghanistan launched after the Sept. 11, 2001, terror attacks never were budgeted and have cost taxpayers more than $1.4 trillion so far. Obama ordered the last troops out of Iraq in December, but the Afghanistan conflict is set to continue through 2014.

Bush also signed legislation in 2003 enacting a prescription drug benefit as part of Medicare, the government health care plan for seniors, a huge entitlement program projected to cost as much as $1.2 trillion over 10 years.

The Troubled Asset Relief Program, the bank bailout program widely loathed by many conservatives, was another Bush-era package. Congress authorized nearly $700 billion for the program at the recommendation of Bush's treasury secretary, former Goldman Sachs executive Henry Paulson, in response to the collapse of Lehman Brothers and the subsequent financial crisis in the fall of 2008. As a presidential candidate, Obama supported the TARP bailout, as did his GOP rival, Sen. John McCain.

Romney shared a deep sense of respect for the Bush family while glancing at the picture in the corner, which featured the faces of the former presidents, George H. W. Bush and George W. Bush.

"I love that picture over there of the two presidents. Father and son," Romney said as reporters were leaving the office. "What a legacy."

__

AP Deputy Director of Polling Jennifer Agiesta in Washington contributed to this report.

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Make A Commitment To Your overall health With A Weight Loss ...

Thursday, March 29th, 2012 at 6:06 pm ?

Hello and welcome. Thank you so much for visiting my blog. If you enjoyed this post please be sure to subscribe to my Blog. Thanks for visiting!

Reality reveals like ?The Biggest Loser? have got inspired thousands of people to lower their idea of exactly what a weekend getaway must be, and instead enroll in one of many quality weight loss fitness getaways obtainable around the country, plus across the globe. And, not everyone that attends these folks is doing so only for the task of slimming down, but are doing so given that they want to up its fitness level, and concentrate for just pampering on their own for a week, or even a weekend.

More strength in a shorter time period

By attending a getaway resort rather than regular weight loss and also fitness vacation, which often lasts a week or more, you get the same higher level of education and conditioning programs, but only for a more intense natural environment. A lot of attendees for these particular programs are more than only those who are morbidly obese, as well as have medical conditions which need them to jump start how much they weigh loss. A rising number of them are individuals who have already incorporated some type of health and fitness into their routines, and are just looking to help tone up and perhaps live through a period of being slack relating to health.

Another popular reason to attend one of these weight-loss fitness getaways is perfect for groups of friends and also business associates to have an powerful weekend of conditioning and bonding through activities. It is not unexpected to see groups of girls arriving to remember some special occasion, like an upcoming wedding, or possibly a corporation sending the salespeople to one on an intense and difficult weekend of exercises designed to bond all of them closer as a team. Largest, these shortened breaks are very effective at completing whatever goals you could have set for yourselves.

Simply how much weight can you get rid of in a single weekend?

A good diet and exercise program which enables you to lose usually from 1 to 3 lbs . a week, in a harmless manner, will see success over time that significantly outdistance the average fad diets at this time in vogue on the market today. Actually on reality shows, contestants only show those amazing outcomes seemingly in a week involving filming because they are at it for at least three weeks prior to the first weigh in. Imagine the outcomes you could achieve in a mere weekend, at the very same level of intensity.

At weight loss vacations in Ny, they were constantly traveling, hiking, and limited to eat only the things they could carry inside their backpacks. Or in Vegas, where you walked in all places and hiked to the Hoover Dam. Or, weight loss vacations in the Caribbean , held completely at the whims of a dedicated crew aboard a luxury crusie ship. Attendees could feed on whatever they wanted, although had to attend almost all scheduled activities to the privilege. This supposed unscheduled stops in harbour cities which might include traveling on foot for miles to see a strong attraction, for hours at a time, only to return and so tired they couldn?t imagine pigging out on a buffet.

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Half of all cancers are preventable: study

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Source: http://news.yahoo.com/half-cancers-preventable-study-181106201.html

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Congress passes stopgap transportation jobs bill (cbsnews)

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Could bombing Iran push it to build the Bomb?

VIENNA (Reuters) - Pre-emptive military strikes aimed at forcing Iran to abandon its nuclear activities may end up having the opposite effect: convincing the Islamic Republic's leaders they need an atomic arsenal to secure their hold on power.

That is the argument from those in the West and elsewhere who say the negative impact of an Israeli or U.S. attack would eventually outweigh any gains - pushing Iran towards a decision that Western intelligence services believe it has not yet taken.

"It is difficult to see a single action more likely to drive Iran into taking the final decision to acquire nuclear weapons than an attack on the country," the foreign ministers of Sweden and Finland said in an opinion piece in the New York Times.

"And once such a decision was made, it would only be a matter of time before a nuclear-armed Iran became a reality," Carl Bildt and Erkki Tuomioja added.

Israel says Iran's nuclear ambitions are a threat to the Jewish state's very existence and that time is running short to stop Tehran taking the irreversible step of acquiring the bomb.

But an attack may delay Iran's nuclear drive only by a few years and would probably lead to an acceleration of the atomic program, the expulsion of U.N. inspectors and the Iranian people rallying around their leaders, the International Crisis Group think-tank said in a report citing unnamed U.S. officials.

"Once U.N. inspectors are expelled, Iran could reconstitute its nuclear infrastructure, this time unambiguously geared to producing a bomb," ICG analyst Ali Vaez told Reuters.

A similar message came from former CIA director Michael Hayden, who said the George W. Bush administration had concluded that a strike on the Islamic Republic's nuclear sites was a bad idea, according to a Foreign Policy magazine blog.

An attack would guarantee the very thing that the West was trying to prevent - "an Iran that will spare nothing to build a nuclear weapon and that would build it in secret", Hayden was quoted as telling reporters and experts in January.

Iran is relatively weak in conventional weaponry, compared to Israel and other Middle Eastern states, and may feel it has little choice but to develop nuclear bombs if "pushed into a corner", said military researcher Pieter Wezeman.

"If Israel or the U.S. would try to attack Iran and its strategic centers and its industry, Iran basically does not have the conventional means to defend itself," Wezeman, of the Stockholm International Peace Research Institute, told Reuters.

"Based on that weakness they are likely to find nuclear arms an interesting option. They don't want to be seen as losers, not internationally and not within Iran."

Any such feeling of military vulnerability in Iran - which often accuses adversaries of plotting to overturn its Islamic Revolution - would be compounded by Israel's assumed nuclear arsenal and the still strong presence of U.S. armed forces in the volatile Gulf region.

TALKS MAY OFFER "BREATHING SPACE"

There is general agreement among Western powers that Iran has already taken steps that would give it the option of becoming a nuclear-armed power, if it so decided.

It has ramped up its uranium enrichment, the U.N. nuclear watchdog said last month, voicing "serious concerns regarding possible military dimensions" to the nuclear activities.

Western experts say Iran now has enough refined uranium -material which can yield energy or weapons, depending on the level of enrichment - for four bombs if processed much further.

Crucially, however, the U.S. administration has concluded that Iranian leaders have not decided whether to actively construct a nuclear weapon, current and former officials have told Reuters.

"The U.S. intel community says with high confidence that Iran has made a capability decision, not a bomb decision," said Jim Walsh, a research associate at the Massachusetts Institute of Technology (MIT). "Bombing them will produce a bomb decision, and that will be very difficult to stop."

Iran expert Trita Parsi said: "You can't convince a country that it doesn't need a nuclear deterrence by bombing it."

But Bruno Tertrais of the Strategic Research Foundation, a French think-tank, said nobody could claim to know the impact of an attack and he suggested it could be difficult for Iran to launch a nuclear weapons bid afterwards.

"Iran would be closely monitored and would then take the risk to be bombed again, before it actually produces deliverable weapons," Tertrais said.

"One needs to differentiate between an Israeli and a U.S. operation: the latter would be bigger, leave few stones unturned, and might very well shake up the foundations of the regime."

Israel has threatened Tehran with pre-emptive strikes if diplomacy fails to stop its nuclear progress. U.S. President Barack Obama says all options are on the table, including possible military action, in dealing with Tehran.

Israel worries that Iran will soon have moved enough of its nuclear program underground as to make it virtually impervious to a unilateral Israeli attack, creating what Defence Minister Ehud Barak has referred to as a "zone of immunity".

But Obama - who has accused U.S. Republican presidential candidates of "beating the drums of war" while failing to consider the consequences - is also encouraging Israel to give sanctions against Iran more time to have an effect.

The Jewish state this week played down the prospect of an imminent attack, saying Iran's nuclear program could still be set back by sanctions and sabotage.

Six world powers and Iran are in mid-April expected to resume long-stalled negotiations aimed at finding a diplomatic resolution to the nuclear dispute, a dialogue which may for now cool speculation of imminent war [ID:nL6E8ES1DU]

"I'm not optimistic on the talks, but I do think they could at the very least open a temporary breathing space for all sides," said Gala Riani of risk consultancy Control Risks.

NUCLEAR DETERRENCE

If Israel in the end decides to strike, Vaez of the International Crisis Group said "it was easy to imagine" that Iran would withdraw from the Non-Proliferation Treaty (NPT), a 1970 pact to prevent the spread of atomic weapons.

Iran's envoy to the U.N. nuclear agency, Ali Asghar Soltanieh, warned this month that any attack by a non-NPT member - Israel - on the nuclear sites of a country that is party to the treaty would inevitably lead to the pact's "collapse."

MIT's Walsh said Iran might need years to recover from an attack but it would not destroy its know-how and would "present a window of opportunity for pro-bomb advocates" in the country.

Short of a full-scale war or occupation, "most military options are oversold as to their ability to end or even significantly delay Iran's nuclear program," the Institute for Science and International Security (ISIS) said.

A vast country, Iran has dispersed its program across many facilities, some whose locations may remain secret.

"An ineffective bombing campaign ... would leave Iran able to quickly rebuild its program and motivate it to launch its own Manhattan Project," the Washington-based think-tank said, referring to the U.S. atomic bomb program in World War Two.

But the view in Israel is that any action that can delay nuclear militarization is beneficial, "because it might maximize opportunities for other events, such as regime change in Iran", the International Crisis Group report said.

Iran, a major oil producer that denies any nuclear weapons aims and officially condemns nuclear weaponry as a "great sin", says it needs uranium enriched to a low level to fuel a planned network of nuclear power plants.

It came under intensifying Western sanctions pressure after the U.N. International Atomic Energy Agency (IAEA), in a November report, presented a trove of intelligence pointing to activities in Iran relevant for nuclear weapons development.

Former IAEA chief Mohamed ElBaradei said he still did not see "incontrovertible evidence" that Iran was working on an atomic bomb and that the question of whether it intends to make one was a matter of opinion and debate.

He said an attack would be a "sure way for Iran to go on a crash course to build nuclear weapons with the full support of the Iranian people ... and with the most catastrophic consequences for the Middle East and the rest of the world."

ElBaradei, who ran the IAEA for 12 years to the end of 2009, was outspoken in his skepticism of Western intelligence after erroneous reports about secret weapons of mass destruction in Iraq were used by the United States to justify the 2003 invasion that overthrew Saddam Hussein.

The risks posed by Iran's nuclear program "need not be hyped," he said in an email to Reuters. "We should by now have learned some lessons from the Iraq disaster."

(Editing by Robin Pomeroy and Mark Heinrich)

Source: http://news.yahoo.com/could-bombing-iran-push-build-bomb-222718667.html

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Rihanna avoids questions about Ashton Kutcher

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Source: http://news.yahoo.com/rihanna-avoids-questions-ashton-kutcher-155806202.html

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Researchers develop new plastics that 'bleed' and heal like human skin

It looks like plastics may not be something for the squeamish in the not-too-distant future. Researchers from the University of Southern Mississippi recently revealed a new type of plastic they've been working on that takes its inspiration from human skin -- it "bleeds" red when it's scratched or cut and then heals itself when it's exposed to light. As Popular Science notes, self-healing plastics aren't something entirely new, but the "bleeding" (achieved using small molecular links or "bridges" that break when the plastic is scratched) is, as is the fact that this plastic an heal itself over and over again in the same spot. What's more, as it's made from water-based copolymers, it's also more environmentally-friendly than other plastics. Of course, it's all a ways from being used in actual products, but the researchers see no shortage of possibilities, including everything from self-healing car fenders to aircraft applications that could warn of problems before they get too severe.

Continue reading Researchers develop new plastics that 'bleed' and heal like human skin

Researchers develop new plastics that 'bleed' and heal like human skin originally appeared on Engadget on Wed, 28 Mar 2012 10:14:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/03/28/researchers-develop-new-plastics-that-bleed-and-heal-like-huma/

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Kat Graham Releases Music Video for "Put Your Graffiti on Me"

Kat Graham has taken a break from casting spells on The Vampire Diaries to cast a net of sexiness all over the Web.

The singer/actress released the official video last night for "Put Your Graffiti on Me," the first track off an album expected to be released some time this year.

Says Graham, who signed with A&M records in February, of the single:

"The song is basically about owning yourself sexually and allowing yourself to be owned too. And having empowerment in that... I'm all about female empowerment and having a song that has this kind of reference."

For more of what's to come on the star's CW thriller, visit The Vampire Diaries spoilers section at TV Fanatic. For a look at this video, just scroll down.

Kat Graham - "Put Your Graffiti On Me" (Official Video)

Source: http://www.thehollywoodgossip.com/2012/03/kat-graham-releases-music-video-for-put-your-graffiti-on-me/

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Southern Africa Food and Drink Report - Bharat Book Bureau ...

The Southern Africa Food & Drink Report features Business Monitor International (BMI)?s market assessment and independent forecasts to end-2016 for food and drink expenditure, consumption, sales, and imports/exports, and for the mass grocery retail sector. The report also includes analyses of major regulatory developments, the background macroeconomic outlook, and competitive landscape comparing national and multinational companies by leading products and services, sales, investments, partners and expansion strategies.?http://www.bharatbook.com/market-researc?

BMI?s Southern Africa Food & Drink Report provides industry professionals and strategists, sector analysts, business investors, trade associations and regulatory bodies with independent forecasts and competitive intelligence on the food and drink industry, and the mass grocery retail market in Angola, Botswana, Mozambique, Namibia and Zambia. Market Research Companies

Key Benefits
* Benchmark BMI?s independent food and drink industry forecasts to end-2016 on Southern Africa to test other views ? a key input for successful budgeting and strategic business planning in the Southern Africa food and drink market.
* Target business opportunities and risks in Southern Africa through our reviews of latest industry trends, regulatory changes, and major deals, projects and investments.
* Exploit latest competitive intelligence on your competitors, partners and clients via our Company Profiles (inc. SWOTs, KPIs and latest activity) and Competitive Landscape Tables.

Executive Summary
Summary of BMI?s key industry forecasts, and views, covering food and drink manufacturing and consumption and the retail market.

Business Environment Ratings
BMI?s Food & Drink Business Environment Ratings provide a country-comparative Risk-Reward Ratings index aimed at investors, food and drink manufacturers and mass grocery retailers.

The ratings methodology makes sophisticated use of over 40 industry, economic and demographic data points.

Industry SWOT Analysis
Analysis of the major Strengths, Weaknesses, Opportunities and Threats within the food, drink and mass grocery retail sectors, and within the broader political, economic and business environment.

Food Forecasts To End-2016
Divided into three sections, BMI?s food chapter provides insight into a market?s food industry, centred on a forecast to end-2016 for the sector. The chapter includes the following elements:

Industry Forecast Scenario ? Historical data series and forecasts to end-2016 for growth of key indicators within a market?s food industry. Including consumption, food consumption as % of GDP, canned food sales, confectionery sales and food and drink imports and exports, among others.

Industry Developments ? A summary of corporate developments, including news on M&As, FDI, expansions, closures and financial results, in addition to analysis and explanation of the latest industry events and how these could influence further investment.

Market Overview ? An overview of the structure of the market, introducing the key players and discussing underlying trends.

Drink Forecasts To End-2016
Segmented the same way as BMI?s food chapter, the drink section provides insight into the market?s drink industry, centred on a forecast to end-2016 for the sector. Forecast indicators include alcoholic and soft drink sales by value, volume and sub-sector and tea and coffee sales, among others.

Mass Grocery Retail Forecasts To End-2016
Segmented the same way as BMI?s food and drink chapters, the mass grocery retail section provides insight into a market?s grocery retail industry, centred on a forecast to end-2016 for the sector. Forecast indicators include mass grocery retail sales by format (including supermarkets, hypermarkets, convenience and discount stores) and a breakdown for the organised retail sector versus the traditional sector, among others.

For more information kindly visit :
Southern Africa Food and Drink Report

Or

Bharat Book Bureau
Tel: +91 22 27810772 / 27810773
Fax: + 91 22 27812290
Email: ?info at bharatbook.com
Website:?www.bharatbook.com
Follow us on twitter:?http://twitter.com/#!/Sandhya3B

Source: http://bharatbook.blogactiv.eu/2012/03/26/southern-africa-food-and-drink-report/

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Shorter telomeres linked to poor cardiovascular outcomes

ScienceDaily (Mar. 25, 2012) ? No one really wants the short end of the stick, in this case the short end of a chromosome. Telomeres, which are DNA-protein complexes at the ends of chromosomes, can be thought of as protein "caps" that protect chromosomes from deteriorating and fusing with neighboring chromosomes.

It is typical for telomeres to shorten as cells divide and chromosomes replicate over time. Now a new study from Brigham and Women's Hospital (BWH) suggests a strong link between telomere shortening and poor cardiovascular outcomes in patients with acute coronary syndrome.

The study is being presented at the American College of Cardiology 2012 Annual Scientific Session, March 24 to 26 in Chicago.

Scientists measured telomere length in 5,044 patients with an acute coronary syndrome who were followed for 18 months.

Scientists evaluated the risk of cardiovascular death or heart attack based on telomere length and other characteristics.

Shorter telomeres were associated with older age, male gender, smoking, prior heart attack and heart failure; although, the correlation between each individual factor and telomere length was modest. Age, for example, only accounts for seven percent of the variability in telomere length.

Telomere length was strongly associated with risk of cardiovascular death or heart attack. Patients with shorter telomeres had the highest risk. This relationship was consistent across various age groups.

"We know that many different genetic and environmental factors, like diabetes, high cholesterol and smoking predispose patients to suffering cardiovascular events," said Christian T. Ruff, MD, MPH, Cardiovascular Division, BWH Department of Medicine, and lead study investigator. "Even when accounting for all of these other known risk factors, patients with short telomeres have an increased risk of having a heart attack or dying from heart disease."

Taking the research findings from bench to bedside, Ruff points out that measuring telomere length may be useful in a clinical setting, providing a sort of predictor for cardiovascular events.

"Telomere shortening may represent some sort of 'biological clock' which integrates the cumulative effect of environmental and genetic stresses on the body, both of which can contribute to cardiovascular events." said Ruff.

The researchers will continue to validate their findings to see if the relationship between telomere length and cardiovascular outcomes holds true in broader populations of patients. They also plan on experimenting on whether the rate of telomere shortening over time also predicts adverse cardiovascular events.

"In the future, we hope to identify clinical, biochemical and genetic characteristics that predict telomere shortening," said Ruff. "We hope to have the ability to determine if therapies and medications that impact these processes may delay telomere attrition and lessen the risk of cardiovascular events in these patients."

This research was supported by a Future Leaders in CV Medical Research Grant, Merck & Co., Inc.

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Story Source:

The above story is reprinted from materials provided by Brigham and Women's Hospital.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/03/120325102840.htm

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Russian banker shot in London 'wanted in Moldova'

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Source: http://news.yahoo.com/russian-banker-shot-london-wanted-moldova-142455162.html

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paul smith glasses frames Real Estate Leasing Rent

It is wise as owners to have a template made to readily build advertisement rental lease agreements. A advertisement rental accession namely a written and binding file is conveys the approval between a attribute employer plus tenant. Involved within the lease agreement are the conditions,paul smith glasses frames, responsibilities plus regulations which the boss as well as tenant are apt imitate The template itself aspiration never need to be changed as every agreement; prefer you?ll need to different the characteristics like rent responsibilities plus property information.
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Source: http://asics.manablog.jp/archives/13485

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World Oil Prices Rise On Falling U.S. Reserves

The price of oil on world commodity exchanges was growing Friday morning as stock inventory in the U.S. declined.

The price of a May futures contract for WTI light sweet crude in electronic trading on Nymex was up 40 cents to $105.75 a barrel by 8:15 Moscow time. The price of a May futures contract for North Sea Brent blend was up 25 cents to $123.39 in London.

Copyright 2012, Golos Rossii. All rights reserved.

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Source: http://www.oilandgaseurasia.com/news/p/0/news/14552/

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Will Wacky Helmet Accessories Trick Kids Into Thinking Safety Is Cool? [Safety]

Even as an adult who understands the risks, I hate wearing a bike helmet, but do it anyways. Kids, however, aren't quite as understanding. So these fake helmet mohawks known as Fohawx are supposed to convince them that safety is cool. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/taIzD4ROKto/will-wacky-helmet-accessories-trick-kids-into-thinking-safety-is-cool

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Russia, a close ally of Syria, to discuss the crisis there with Kofi Annan

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Source: http://news.yahoo.com/russia-close-ally-syria-discuss-crisis-kofi-annan-164345835.html

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Oil surges on Iran?s report

Oil surged almost $3 dollar to the highest of $108.22 from the lowest at $105.15 on news from Reuters showing that Iranian oil exports will fall by 300K barrels a day as a result to the tighter sanctions, fueling supply worries; and as computer buying orders were triggered.

Crude is trading as of this writing around the $107.10. Meanwhile Brent is trading around the $125.10 level after rising as much as 1.61% during today's session.

Source: http://www.ibtimes.com/articles/318631/20120323/oil-surges-on-iran-rsquoreport.htm

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Facebook Photos Now Viewable In Fullscreen, Higher Resolution

Starting today Facebook is allowing Chrome and Firefox users to ditch the black background and comments sidebar that surround photos and view them fullscreen by clicking an expansion arrow in the top right. It also now automatically shows photos at maximum resolution, which is the 2048 x 2048 pixel max upload size, and?can be up to 4X bigger on large displays. Facebook has improved the sRGB color profile of photos so that colors appear more vivid and faithful without loading slower. Before now, Facebook photos could only be viewed at roughly 3/4 of your screensize. Today's updates will encourage high-res uploads, attract more professional photographers, and make the world's most popular photo sharing service where 250 million photos are uploaded a day a better experience for everyone.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/ZCfPwOPWXMA/

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anabegins: 2012 Intention First Quarter Results: Motherhood

This one is much more qualitative and thus harder to measure success vs. failure so I gave myself a wishy-washy grade.

Motherhood
Original intention:? fun. I want to infuse my home and family with love and laughter
Grade: B

This deserves a B because I am consciously working on it, but far from perfect. When things start to go awry (in that every-day sort of way, when nothing is really wrong, just whinier, jumpier, and grosser than I'd like), I remind myself to "just have fun".? Distraction is a good technique for dealing with kids & adults alike (just ask a certain political party....).? And saying "Yes" more often isn't going to turn my kids into deviants.? I mean, doesn't music, crackers, or a sticker make?everyone's life a little brighter?

My enemy in this is also my dearest ally---my to-do list. There are definitely times (weekday evenings specifically) where I shove aside fun to plow through my chores. I miss my boys all day yet when we all get home I half-ignore them as I rush here & there making lunches, washing bottles, and starting laundry. Sure, all of this can be done after they go to bed but that end-of-the-day alone time is so so precious to me that I try to maximize it by completing the must-dos earlier in the evening...at the expense of giving my full attention to my children.

So I'm going to add to this intention---my motherhood goals will include having fun and focus. And the to-do list gets put on hold from 6-8 pm.

Source: http://ana-begins.blogspot.com/2012/03/2012-intention-first-quarter-results_21.html

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